Custom Peptides
Cayman Chemical PSB-1115potasIum salt 10mg
An adenosine A2B receptor antagonist (Ki = 53.4 nM); selective for A2B over A1 and A2A receptors, which have Ki values of 2,200 and 24,000 nM, respectively; selective for A2B over the A3 receptor, which is inhibited only 14% at a concentration of 10 µM; pre-treatment of rat trachea reduces relaxation induced by repeated dosing of the non-selective adenosine agonist NECA
Cayman Chemical NoctadecnoylLHomoserIn l 10mg
One of four lipophilic, long acyl side-chain bearing AHLs produced by the LuxI AHL synthase homolog SinI involved in quorum sensing signaling in strains of S. meliloti, a nitrogen-fixing bacterial symbiont of the legume M. sativa
Cayman Chemical Unoproston Isopropyl esTR 10mg
An ocular hypotensive agent, a prodrug form of unoprostone, and a derivative of PGF2α; inhibits endothelin-1-induced contractions in isolated porcine retinal arterioles at 1 nM; inhibits indomethacin-induced increases in intraocular pressure and increases PGE2 levels in the aqueous humor and aqueous humor outflow in rabbits when applied topically at 0.12% v/v
Cayman Chemical 6CarytetramthylrhodamIn 10mg
A fluorescent dye; ex/em = 543/572 nm, respectively; has commonly been used for the covalent labeling of oligonucleotides for DNA analysis; has been used in various DNA-protein binding studies, DNA FRET experiments, and as a standard reporter or quencher dye in RT-PCR
Cayman Chemical Stearoyl EthnolamIde 10mg
A member of the family of fatty N-acyl ethanolamines collectively called anandamides and the most abundant of several fatty acid ethanolamides produced by the PLD hydrolysis of mouse neuroblastoma cell membrane phospholipids; its specific role in the cannabinergic system remains to be elucidated
Cayman Chemical N-ArachIdonyl DopamIn 10mg
An arachidonoyl amino acid and CB1 receptor agonist (Ki = 250 nM in rat brain membranes, which highly express CB1 receptors); selective for CB1 over CB2 receptors (Ki = 12,000 nM in rat spleen membranes, which highly express CB2 receptors); induces intracellular calcium mobilization in N18TG2 neuroblastoma cells (EC50 = 0.7 µM); inhibits the proliferation of MCF-7 breast cancer cells (IC50 = 0.25 µM); induces hypothermia, catalepsy, hypolocomotion, and analgesia in mice at 10 mg/kg
Cayman Chemical Montropen 10mg
An iridoid glycoside with diverse biological activities; increases cell viability and migration of BM-EPCs from 0.1-1,000 μM; inhibits apoptosis and reduces levels of MMP-3 and MMP-13 in chondrocytes; inhibits LPS-induced nuclear translocation of NF-κB and reduces COX-2, iNOS, NF-α, and IL-1β mRNA expression in RAW 264.7 cells; reduces colonic MPO activity, COX-2 and iNOS mRNA expression, and disease severity in a mouse model of DSS-induced ulcerative colitis at 100 and 200 mg/kg; increases bone mineral content, bone mineral density, and improves bone microstructure in ovariectomized mice at 40 and 80 mg/kg; reduces acetic acid-induced writhing in mice and carrageenan-induced paw edema in rats at 20 and 30 mg/kg; decreases macrophage infiltration and wound healing time and increases blood vessel formation in a rat model of wound healing
Cayman Chemical 1PalmItoyl2LInoleoyl3Ste 10mg
A triacylglycerol; has been found in mature human milk and various plant oils
Cayman Chemical pnItroCyclIc PIfIthrIna 10mg
A cell-permeable form of cyclic PFT-α; 10-fold more active that PFT-α in protecting cortical neurons exposed to etoposide (ED50 = 30 nM); not active in vivo
Cayman Chemical 17phenyl TRNor PROSGlndI 10mg
A form of 17-phenyl trinor PGF modified with a cyclohexane moiety at the alpha carbon; insoluble in aqueous media, soluble in organic solvents; activity at the FP receptor has not been evaluated
Cayman Chemical Ctrus maxa peel Mernzn 10mg
A coumarin with diverse biological activities; cytotoxic to NSCLC-N6 and KB cancer cells (IC50s = 14.6 and 12.3 UG/ml, respectively); increases the latency to paw withdrawal in the hot plate test and reduces xylene-induced EAr edema in mice at 10 mg/kg; decreases carrageenan-induced paw edema in rats at 10 mg/kg
Cayman Chemical Chromn 1hydrochLRIde hydr 10mg
A ROCK2 inhibitor (IC50 = 50s = 1,740 and 127 nM, respectively); inhibits phosphorylation of MLC in a cell-based assay (IC50 = <4 nM)
Cayman Chemical AdrenorphInhumnmousera 10mg
An octapeptide agonist of μ-opioid receptors; selectively binds to μ-opioid receptors over κ- and δ-opioid receptors (Kis = 0.12, 0.248, and 2.65 nM, respectively); increases the latency to paw licking in the hot plate test in mice at 6.1 nmol/animal, i.c.v.; induces respiratory depression in mice and rabbits (ED50s = 6 and 71.1 nmol/animal, respectively)